Vaccinations:
| Hepatitis A | Recommended for all travelers |
| Typhoid | Recommended for all travelers |
| Yellow fever | Recommended for all travelers who are visiting the provinces of Darien, Kunayala (San Blas), and Panama, excluding the Canal Zone, Panama City, and the San Blas islands. Required for all travelers arriving from a yellow-fever-infected country in Africa or the Americas. |
| Hepatitis B | Recommended for all travelers |
| Rabies | For travelers spending a lot of time outdoors, or at high risk for animal bites, or involved in any activities that might bring them into direct contact with bats |
| Measles, mumps, rubella (MMR) | Two doses recommended for all travelers born after 1956, if not previously given |
| Tetanus-diphtheria | Revaccination recommended every 10 years |